Maria Castedo Selected Research

Tetraploidy

1/2017	Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells.
1/2016	Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.
2/2014	Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention.
5/2013	Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.
2/2013	Immunosurveillance against tetraploidization-induced colon tumorigenesis.
1/2013	An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells.
1/2013	Transgenerational cell fate profiling: a method for the graphical presentation of complex cell cycle alterations.
7/2010	Involvement of p38alpha in the mitotic progression of p53(-/-) tetraploid cells.
5/2009	p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis.
4/2009	Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Maria Castedo Research Topics

Disease

27	Neoplasms (Cancer) 01/2022 - 03/2002
17	Tetraploidy 01/2017 - 06/2006
8	Carcinoma (Carcinomatosis) 01/2021 - 05/2004
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 11/2007
6	Lung Neoplasms (Lung Cancer) 01/2022 - 03/2002
6	Polyploidy 02/2014 - 05/2007
3	Starvation 01/2021 - 01/2018
3	Aneuploidy (Aneuploid) 01/2017 - 05/2004
1	Overnutrition 01/2021
1	Malnutrition (Nutritional Deficiencies) 01/2021
1	Obesity 01/2021
1	Weight Gain 01/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2018
1	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 11/2014
1	Colonic Neoplasms (Colon Cancer) 02/2014
1	Rupture 03/2013
1	Hyperthermia 02/2013
1	Hypoxia (Hypoxemia) 02/2013
1	Carcinogenesis 01/2013
1	Genomic Instability 07/2010
1	Chromosomal Instability (Chromosome Stability) 12/2007

Drug/Important Bio-Agent (IBA)

13	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 06/2006
12	DNA (Deoxyribonucleic Acid)IBA 05/2013 - 05/2004
7	Proteins (Proteins, Gene)FDA Link 11/2014 - 05/2003
4	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2018 - 03/2013
4	CalreticulinIBA 05/2013 - 01/2007
3	CaspasesIBA 01/2016 - 10/2009
3	Etoposide (VP 16)FDA LinkGeneric 01/2007 - 03/2002
2	AntimetabolitesIBA 01/2018 - 01/2018
2	Cytochromes c (Cytochrome c)IBA 01/2016 - 03/2013
2	Antineoplastic Agents (Antineoplastics)IBA 11/2014 - 03/2013
2	CarcinogensIBA 05/2013 - 09/2012
2	Vitamin B 6IBA 02/2013 - 08/2012
2	pyrazolanthroneIBA 01/2013 - 06/2012
2	Phosphotransferases (Kinase)IBA 01/2013 - 07/2008
2	Cytotoxins (Cytolysins)IBA 08/2012 - 12/2006
2	Epothilones (Epothilone)IBA 01/2010 - 07/2008
2	CamptothecinIBA 12/2006 - 06/2006
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2006 - 06/2006
1	niraparibIBA 01/2022
1	Poly (ADP-Ribose) Polymerase-1IBA 01/2022
1	Inducible T-Cell Co-Stimulator ProteinIBA 01/2022
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 01/2021
1	Acyl Coenzyme A (Acyl CoA)IBA 01/2021
1	Carrier Proteins (Binding Protein)IBA 01/2021
1	Poly Adenosine Diphosphate RiboseIBA 01/2021
1	Pyridoxal KinaseIBA 01/2021
1	Diazepam Binding InhibitorIBA 01/2021
1	5-methoxy-methylindoleacetic acid (DBI)IBA 01/2021
1	EnzymesIBA 01/2019
1	Aldehyde DehydrogenaseIBA 01/2019
1	Lipase (Acid Lipase)FDA Link 01/2019
1	NucleosidesIBA 01/2018
1	Glutamine (L-Glutamine)FDA Link 01/2018
1	NucleotidesIBA 01/2018
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 01/2018
1	Caspase 2IBA 01/2017
1	Protein Kinases (Protein Kinase)IBA 01/2016
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2014
1	Adenine FDA LinkGeneric 11/2014
1	NAD (NADH)IBA 11/2014
1	obatoclaxIBA 11/2014
1	Nicotine FDA Link 11/2014
1	SalicylatesIBA 02/2014
1	Antimitotic AgentsIBA 02/2014
1	ResveratrolIBA 02/2014
1	ProdrugsIBA 02/2014
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 02/2014
1	AMP-Activated Protein KinasesIBA 02/2014
1	AntioxidantsIBA 02/2013
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 02/2013
1	Glutathione (Reduced Glutathione)IBA 08/2012
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 06/2012
1	2- (4- morpholinoanilino)- 6- cyclohexylaminopurineIBA 06/2012
1	Mitogen-Activated Protein Kinase 14IBA 07/2010
1	Mitogen-Activated Protein KinasesIBA 07/2010
1	Tumor Suppressor Protein p53IBA 07/2010
1	Apoptosis Regulatory ProteinsIBA 10/2009
1	2- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphateIBA 10/2009
1	Aurora Kinase BIBA 10/2009
1	CHIR-124IBA 04/2009
1	Small Interfering RNA (siRNA)IBA 04/2009
1	dimethylenastronIBA 04/2009
1	KinesinsIBA 04/2009
1	Histones (Histone)IBA 04/2009
1	Checkpoint Kinase 1IBA 07/2008
1	7-hydroxystaurosporine (UCN 01)IBA 07/2008
1	sagopiloneIBA 07/2008
1	TubulinIBA 07/2008
1	Paclitaxel (Taxol)FDA LinkGeneric 07/2008
1	p38 Mitogen-Activated Protein KinasesIBA 07/2008
1	endonuclease GIBA 05/2007
1	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2007
1	StaurosporineIBA 12/2006
1	Hydroxyurea (Hydrea)FDA LinkGeneric 12/2006

Therapy/Procedure

5	Drug Therapy (Chemotherapy) 01/2021 - 12/2006
2	Therapeutics 11/2014 - 01/2013
2	Radiotherapy 12/2007 - 12/2006
1	Chemoprevention 02/2014
1	Subcutaneous Injections 02/2013